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Fertility

Can adenomyosis cause miscarriage?

The short answer

Adenomyosis may contribute to miscarriage for some patients, but many people with adenomyosis have healthy pregnancies. Changes in the uterine muscle and environment may affect implantation and early placental development, and risk varies from person to person.

Adenomyosis can be associated with a higher risk of pregnancy complications, and it may contribute to miscarriage for some patients. But it’s not a guarantee, and many people with adenomyosis go on to have healthy pregnancies. It can matter because adenomyosis changes the uterine muscle and uterine environment, which may affect implantation and early placental development through inflammation and abnormal uterine contractions.

Risk isn’t the same for everyone. Outcomes often depend on the pattern of disease (focal adenomyoma versus diffuse adenomyosis), how much of the uterine wall/junctional zone is affected, and whether adenomyosis overlaps with endometriosis. This overlap is common and can compound fertility and pregnancy challenges. If you’ve experienced infertility, recurrent pregnancy loss, or repeated implantation failure, our team can help evaluate whether adenomyosis and coexisting endometriosis may be part of the picture and walk you through fertility-sparing options, including when surgery to remove a focal adenomyoma may be realistic versus when other approaches make more sense.

Where to go from here

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Worried About Adenomyosis & Pregnancy?

We understand the concerns around adenomyosis and miscarriage risk. Our specialists can help evaluate your condition and support your fertility journey with personalized care.

Questions people ask next

All fertility questions
  • Can adenomyosis affect fertility or pregnancy?

    Yes, adenomyosis can affect both fertility and pregnancy. It may interfere with implantation and is associated with higher risks of miscarriage and preterm birth, with diffuse adenomyosis often having a greater impact than focal disease.

  • Can focal adenomyosis affect fertility or miscarriage risk?

    Yes, focal adenomyosis can affect fertility and miscarriage risk, especially when a lesion distorts the uterine cavity or interferes with implantation. Not all focal adenomyosis behaves the same: smaller nodules farther from the cavity may have less impact.

  • Does diffuse adenomyosis affect fertility and miscarriage risk?

    Diffuse adenomyosis can affect fertility by changing uterine contractions and the environment where an embryo implants. For some patients, this can contribute to difficulty conceiving and may be associated with a higher risk of early miscarriage.

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Lotus Endometriosis Institute provides California-based surgical evaluation and advanced excision care for patients with suspected endometriosis, adenomyosis, complex pelvic pain, and related conditions.


Many patients contact us from outside California to learn whether traveling for in-person evaluation and possible surgery may be appropriate.

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(424) 255-1340

(805) 920-0909

Fax: (805) 935-4338

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

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Monday - Friday

Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420