Is endometriosis an autoimmune disease?

No—endometriosis is not currently classified as an autoimmune disease. That said, it often involves immune system dysregulation, including chronic inflammation and changes in how the body responds to endometrial-like tissue outside the uterus.

Because of these immune features, some patients with endometriosis also have autoimmune conditions, and overlapping symptoms can blur the picture. If you’re dealing with persistent pelvic pain plus systemic symptoms like fatigue, joint pain, rashes, or gastrointestinal changes, our team can help sort out what may be driven by endometriosis versus a coexisting condition and map out an appropriate evaluation plan.