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Interstitial Cystitis

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Endometriosis may overlap with interstitial cystitis/bladder pain syndrome (IC/BPS). Discover symptoms, diagnostic pathways, and evidence-based treatments and self-care to reduce flares, protect bladder health, and ease pelvic pain.

Overview

Interstitial cystitis/bladder pain syndrome (IC/BPS) causes bladder‑centered pain, pressure, or burning with urinary frequency and urgency, typically with sterile urine cultures. Symptoms often worsen with bladder filling and ease after voiding, and can flare with stress, sex, certain foods, or around menstruation. IC/BPS commonly coexists with endometriosis through shared pain mechanisms and pelvic floor hypertonicity, making evaluation of Pelvic Floor Dysfunction important. It differs from structural disease in Bladder Endometriosis, which may cause cyclical hematuria or visible lesions; both can occur together and need tailored care.


Learn how clinicians confirm IC/BPS using history, bladder diaries, pelvic exam, and selective testing to rule out infection, stones, or malignancy; cystoscopy is reserved for red flags or to identify Hunner lesions. Explore stepwise care that starts with bladder training, individualized nutrition strategies, stress regulation, and Pelvic Floor PT, then progresses to medications and intravesical therapies when needed. Guidance also covers flare planning, sex and exercise modifications, and how findings from Diagnostics & Imaging inform care when endometriosis is present.

Common Questions

  • Can endometriosis and interstitial cystitis happen together?

    Yes, endometriosis and interstitial cystitis (bladder pain syndrome) can occur together and cause similar symptoms, such as urgency, frequency or burning. When both are present, treating only endometriosis may not fully relieve bladder-driven pain.

  • Can endometriosis cause vulvar burning or rawness?

    Yes, endometriosis can contribute to vulvar burning or rawness indirectly through pelvic floor muscle overactivity and nerve sensitization. Bladder pain syndromes and other vulvovaginal conditions can also coexist, so endometriosis may not be the only cause.

  • Can endometriosis cause bladder pressure at night?

    Yes, endometriosis can contribute to bladder pressure at night, especially when it involves or irritates the bladder surface or wall. Normal urine tests or negative cultures don’t rule it out, but other conditions can cause similar symptoms.

  • Can adenomyosis cause bladder pain or spasms?

    Yes, adenomyosis can be associated with bladder pain, pressure, and spasm-like sensations, even though it stays within the uterine muscle. An inflamed uterus can cause pain that feels like bladder pain, but bladder symptoms can also point to a separate, overlapping condition.

Reach Out

Have a question?

Lotus Endometriosis Institute provides California-based surgical evaluation and advanced excision care for patients with suspected endometriosis, adenomyosis, complex pelvic pain, and related conditions.


Many patients contact us from outside California to learn whether traveling for in-person evaluation and possible surgery may be appropriate.

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(424) 255-1340

(805) 920-0909

Fax: (805) 935-4338

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

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Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420