Fertility
Does endometriosis increase miscarriage risk?
The short answer
Yes, endometriosis is associated with a modest increase in miscarriage risk, particularly in the first trimester. Most pregnancies in people with endometriosis are successful, and age, pregnancy history and other uterine factors matter for individual risk.
Yes, endometriosis is associated with a modest increase in miscarriage risk, particularly in the first trimester. In large pooled studies, the increase is usually described as a relative risk around 1.2–1.7. It can vary depending on factors like whether pregnancy occurs spontaneously or with fertility treatment.
Even with that increase, most pregnancies in people with endometriosis are successful. What matters most for each person is the full picture: age, prior pregnancy history, and whether adenomyosis or other uterine factors are also present. If you’ve had losses or are planning pregnancy and want an individualized assessment, our team can review your history and imaging, discuss what this risk may mean for you, and talk through options that may help support your goals.
Where to go from here
Understand it, compare it with what you're feeling, then talk it through with us.
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Worried About Miscarriage Risks?
Endometriosis can slightly raise miscarriage risk, but many pregnancies succeed. Our specialists can guide you through personalized fertility care and support your journey.
Questions people ask next
All fertility questionsDoes endometriosis make pregnancy high risk?
Most people with endometriosis have healthy pregnancies, but it can be associated with a higher likelihood of certain complications. These include placenta previa, preterm birth, bleeding during pregnancy and cesarean delivery. Risk is not the same for everyone.
Can adenomyosis cause miscarriage?
Adenomyosis may contribute to miscarriage for some patients, but many people with adenomyosis have healthy pregnancies. Changes in the uterine muscle and environment may affect implantation and early placental development, and risk varies from person to person.
Does endometriosis affect egg quality or implantation?
Endometriosis can affect both egg quality and implantation. In the ovaries, especially with ovarian endometriomas, inflammation may affect how eggs mature, while changes in the uterine lining may make it less receptive to implantation.
How do autoimmune conditions affect fertility and pregnancy in endometriosis?
Autoimmune conditions can add inflammation that may affect ovulation, implantation, and early pregnancy stability alongside endometriosis. In our experience, outcomes often improve when the condition is identified and well-controlled before trying to conceive.
Further reading
Endometriosis and Miscarriage: What Research Suggests
Learn how endometriosis may affect miscarriage risk, the roles of inflammation, hormones, and surgery, what current studies show, and ways to manage fertility.
Adenomyosis, Endometriosis, and Pregnancy: What Patients Need to Know
Explore how adenomyosis affects pregnancy and fertility with endometriosis. Get trusted research insights and advice for your care team.
Fertility-Sparing Treatment for Adenomyosis: Pregnancy Chances, Symptom Relief, and Pregnancy Risks
Weigh pregnancy chances, symptom relief, and risks after fertility-sparing adenomyosis treatment. Compare adenomyomectomy vs HIFU, RFA, UAE: when to add hormones
