Do I need extra cancer screening with endometriosis or adenomyosis?

There is not a universal cancer-screening program recommended solely for endometriosis or adenomyosis, but that does not mean cancer risk should be ignored. Endometriosis is not cancer, and most people with it will never develop cancer, yet research does suggest an increased risk of certain ovarian cancers, which is why individual risk assessment matters.

Tests such as CA-125 or CA19-9 are not reliable routine screening tools by themselves, because they can be elevated for many non-cancer reasons, including endometriosis itself. Instead, the right next step depends on your personal risk profile—especially if you have a strong family history of ovarian, breast, uterine, or colon cancer, a known or suspected genetic predisposition, an endometrioma, deep infiltrating disease, or new concerning symptoms.

In those situations, closer evaluation, imaging, follow-up, and sometimes genetic counseling or testing may be appropriate. Our team can help you understand your individual risk and decide whether additional evaluation makes sense.