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You suspect you may have endometriosis or adenomyosis

Why does pelvic nerve pain persist between periods or spread?

Topic:Symptoms
Affected areas:pelvicbacksystemic

When pain repeats over time, the nervous system can become sensitized—meaning it starts to amplify signals and interpret even mild input as significant pain. That can make symptoms persist between periods and sometimes feel like they’re spreading beyond the original area, even when hormone-driven inflammation is lower.


In the pelvis, muscle guarding (especially in the pelvic floor) and shared nerve pathways between organs can keep the pain cycle going through “cross-talk,” so bladder, bowel, vulvar, hip, or low-back discomfort may appear connected. In many cases, lasting relief requires addressing both the underlying driver (like endometriosis or adenomyosis) and the nervous system and muscle response that developed around it. Our team can help you sort out what pattern fits your symptoms and discuss a plan that targets the source of pain while also calming sensitization over time.

An illustration of a female sitting down, hunched over in discomfort.

Think You Might Have Endometriosis?

If you suspect endometriosis or adenomyosis may be causing your symptoms, our specialists can provide expert evaluation and guidance on next steps.

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Dr. Steven Vasilev delivers best-in-class endometriosis guidance and a personalized treatment plan—built on evidence and your unique biology.


Led by Steven Vasilev, MD—an internationally recognized endometriosis specialist & MIGS surgeon—Lotus Endometriosis Institute is virtual-forward, with many patients traveling nationally for care. Clinical evaluation and surgical treatment are provided in California.

Santa Monica, CA

2121 Santa Monica Blvd, Santa Monica, CA 90404

Operating Hours

8:00 am - 5:00 pm
Monday - Friday

Arroyo Grande, CA

154 Traffic Way, Arroyo Grande, CA 93420