Progesterone or baby aspirin to prevent miscarriage?

Progesterone support is commonly used after IVF, and it may be helpful for some people who have early pregnancy bleeding and a history of prior miscarriages. However, using progesterone routinely for everyone with a positive pregnancy test hasn’t consistently been shown to prevent miscarriage, so the decision is usually based on your specific history and how the pregnancy was conceived.

Low-dose (“baby”) aspirin is most clearly beneficial when recurrent loss is linked to antiphospholipid syndrome, often as part of a coordinated plan that may also include anticoagulation. For unexplained miscarriages, aspirin hasn’t reliably improved outcomes, and using it without a clear indication can add unnecessary risk or confusion. Our team can review your prior losses, labs, and fertility treatment details to recommend an approach that fits your situation—reach out to schedule a consultation if you’d like a personalized plan.